1. 首页
  2. 抗体
  3. 正文

BD IMag- Anti-Human CD19 Magnetic Particles - DM_BD Pharmingen

艾美捷科技 • 2025年08月20日 10:58:57 • 抗体 • 阅读 24 • 标签
产品信息
抗原名称
CD19
宿主
Mouse IgG1, κ
简单描述
BD IMag™ anti-human CD19 Particles - DM are magnetic nanoparticles that have monoclonal antibody conjugated to their surfaces. These particles are optimized for the positive selection or depletion of CD19-bearing leukocytes using the BD IMag™ Cell Separation Magnet. CD19 is expressed during all stages of B-cell differentiation and maturation, except plasma cells. CD19 is also present on follicular dendritic cells. It is not found on T cells or on normal granulocytes.
商品描述
HIB19 BD IMag™ anti-human CD19 Particles - DM are magnetic nanoparticles that have monoclonal antibody conjugated to their surfaces. These particles are optimized for the positive selection or depletion of CD19-bearing leukocytes using the BD IMag™ Cell Separation Magnet. CD19 is expressed during all stages of B-cell differentiation and maturation, except plasma cells. CD19 is also present on follicular dendritic cells. It is not found on T cells or on normal granulocytes.
同种型
Mouse IgG1, κ
克隆号
克隆 HIB19 (RUO)
应用
实验应用
Cell separation (Routinely Tested)
反应种属
Human (QC Testing)
目标/特异性
CD19
背景
别名
B4; B-lymphocyte antigen CD19; Leu-12
制备和贮存
存储溶液
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
文献
文献
研发参考(6) 1. Bradbury LE, Goldmacher VS, Tedder TF. The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13. J Immunol. 1993; 151(6):2915-2927. (Biology). 2. Favaloro EJ, Moraitis N, Koutts J, Exner T, Bradstock KF. Endothelial cells and normal circulating haemopoietic cells share a number of surface antigens. Thromb Haemost. 1989; 61(2):217-224. (Biology). 3. Knapp W. W. Knapp .. et al., ed. Leucocyte typing IV : white cell differentiation antigens. Oxford New York: Oxford University Press; 1989:1-1182. 4. Nadler LM, Anderson KC, Marti G, et al. B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes. J Immunol. 1983; 131(1):244-250. (Biology). 5. Schlossman SF. Stuart F. Schlossman .. et al., ed. Leucocyte typing V : white cell differentiation antigens : proceedings of the fifth international workshop and conference held in Boston, USA, 3-7 November, 1993. Oxford: Oxford University Press; 1995. 6. Uckun FM, Muraguchi A, Ledbetter JA, et al. Biphenotypic leukemic lymphocyte precursors in CD2+CD19+ acute lymphoblastic leukemia and their putative normal counterparts in human fetal hematopoietic tissues. Blood. 1989; 73(4):1000-1015. (Biology).
数据库链接
Entrez-Gene ID
930

参考图片

Positive selection and depletion of human CD19-positive PBMC. Leukocytes were labeled with BD IMag™ anti-human CD19 Particles - DM (Cat. No. 551520) as described in the protocol. After labeling, the cells were separated using the BD IMag™ Cell Separation Magnet (Cat. No. 552311), and the negative (CD19-) and positive (CD19+) fractions were collected. Please refer to the Separation Flow Chart to identify the separated cell populations represented in this figure. For flow cytometric analysis, fresh PBMC (left panel), the negative fraction (middle panel) and the positive fraction (right panel) were stained with PE Mouse Anti-Human CD19 (Cat. No. 555413) and APC Mouse Anti-Human CD3 (Cat. No. 555335). The percent CD19+ cells in each sample is given.

Positive selection and depletion of human CD19-positive PBMC. Leukocytes were labeled with BD IMag™ anti-human CD19 Particles - DM (Cat. No. 551520) as described in the protocol. After labeling, the cells were separated using the BD IMag™ Cell Separation Magnet (Cat. No. 552311), and the negative (CD19-) and positive (CD19+) fractions were collected. Please refer to the Separation Flow Chart to identify the separated cell populations represented in this figure. For flow cytometric analysis, fresh PBMC (left panel), the negative fraction (middle panel) and the positive fraction (right panel) were stained with PE Mouse Anti-Human CD19  (Cat. No. 555413) and APC Mouse Anti-Human CD3   (Cat. No. 555335). The percent CD19+ cells in each sample is given.

文档下载: W 导出为BD IMag- Anti-Human CD19 Magnetic Particles - DM_BD Pharmingen.doc文档

本文来自投稿，不代表本人立场，如若转载，请注明出处：http://www.iamyjet.com/kangti/8981.html

赞 (24)
打赏 微信扫一扫
« 上一篇 2025年08月20日 10:57:52
下一篇 » 2025年08月20日 10:59:30

相关推荐

×
(function(){ var src = (document.location.protocol == "http:") ? "http://js.passport.qihucdn.com/11.0.1.js?1d7dde81dc0903e04d3ac0b9599444f6":"https://jspassport.ssl.qhimg.com/11.0.1.js?1d7dde81dc0903e04d3ac0b9599444f6"; document.write('<\/mip-script>'); })(); (function(){ var bp = document.createElement('script'); var curProtocol = window.location.protocol.split(':')[0]; if (curProtocol === 'https') { bp.src = 'https://zz.bdstatic.com/linksubmit/push.js'; } else { bp.src = 'http://push.zhanzhang.baidu.com/push.js'; } var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(bp, s); })();