BD Pharmingen- PE Rat Anti-Mouse V-4 T-Cell Receptor

BD Pharmingen- PE Rat Anti-Mouse V-4 T-Cell Receptor_BD Pharmingen

艾美捷科技 • 2025年08月21日 10:11:26 • 抗体 • 阅读 7 • 标签

产品信息

荧光素标记

抗原名称

TCR Vβ4

宿主

Rat SD, also known as Sprague-Dawley (outbred) IgG2b, κ

免疫原

KT4 B10.D2 mouse T-cell clone I3

简单描述

The KT4 antibody specifically recognizes the Vβ4 T-cell Receptor (TCR) of mice having the a ( e.g ., C57BR, C57L, SJL, SWR), b ( e.g ., A, AKR, BALB/c, CBA, C3H/He, C57BL, C58, DBA/1, DBA/2), and c ( e.g ., RIII) haplotypes of the Tcrb gene complex. Vβ4 TCR-bearing cells are among the CD4+ autoreactive T cells which induce autoimmune thyroiditis after elimination of regulatory (CD5-bright) T-cell subsets. Plate-bound KT4 antibody activates Vβ4 TCR-bearing T cells.

商品描述

KT4 The KT4 antibody specifically recognizes the Vβ4 T-cell Receptor (TCR) of mice having the a ( e.g ., C57BR, C57L, SJL, SWR), b ( e.g ., A, AKR, BALB/c, CBA, C3H/He, C57BL, C58, DBA/1, DBA/2), and c ( e.g ., RIII) haplotypes of the Tcrb gene complex. Vβ4 TCR-bearing cells are among the CD4+ autoreactive T cells which induce autoimmune thyroiditis after elimination of regulatory (CD5-bright) T-cell subsets. Plate-bound KT4 antibody activates Vβ4 TCR-bearing T cells.

同种型

Rat SD, also known as Sprague-Dawley (outbred) IgG2b, κ

克隆号

克隆 KT4 (RUO)

浓度

0.2 mg/ml

产品详情

R-Phycoerythrin (PE), is part of the BD family of Phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 496 nm and 566 nm and an emission maximum (Em Max) at 576 nm. PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 575/26-nm bandpass filter). As PE is excited by multiple lasers, this can result in cross-laser excitation and fluorescence spillover on instruments with various combinations of Blue, Green, and Yellow-Green lasers. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

格式:PE

激发源:Yellow-Green 488 nm, 532 nm, 561 nm

最多激发源:496 nm, 566 nm

最多发射源:576 nm

应用

实验应用

Flow cytometry (Routinely Tested)

反应种属

Mouse (QC Testing)

目标/特异性

TCR Vβ4

制备和贮存

存储溶液

Aqueous buffered solution containing ≤0.09% sodium azide.

保存方式

Aqueous buffered solution containing ≤0.09% sodium azide.

文献

研发参考(3) 1. Katz JD, Benoist C, Mathis D. T helper cell subsets in insulin-dependent diabetes. Science. 1995; 268(5214):1185-1188. (Biology). 2. Sugihara S, Fujiwara H, Shearer GM. Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. Characterization of thyroiditis-inducing T cell lines and clones derived from thyroid lesions. J Immunol. 1993; 150(2):683-694. (Biology). 3. Tomonari K, Lovering E, Spencer S. Correlation between the V beta 4+ CD8+ T-cell population and the H-2d haplotype. Immunogenetics. 1990; 31(5-6):333-339. (Immunogen).

BD Pharmingen- PE Rat Anti-Mouse V-4 T-Cell Receptor_BD Pharmingen

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