产品信息
宿主
Rat LOU, also known as Louvain, LOU/C, LOU/M IgG1, κ
免疫原
Pooled BALB/c and C57BL/6 mouse Ig
简单描述
The R19-15 antibody recognizes an epitope in the CH3 domain of mouse IgG2a, with strong reactivity to the
Igh-I[a]
allotype and weaker reactivity to
Igh-I[b]
. It does not react with other Ig isotypes. Molecular genetic analyses suggest that the
Igh-I[b]
allele, which encodes
IgG2a[b]
,
is derived from a locus found in several wild mouse subspecies, but not domestic mice, which encodes the IgG2c isotype.
商品描述
R19-15
The R19-15 antibody recognizes an epitope in the CH3 domain of mouse IgG2a, with strong reactivity to the
Igh-I[a]
allotype and weaker reactivity to
Igh-I[b]
. It does not react with other Ig isotypes. Molecular genetic analyses suggest that the
Igh-I[b]
allele, which encodes
IgG2a[b]
,
is derived from a locus found in several wild mouse subspecies, but not domestic mice, which encodes the IgG2c isotype.
同种型
Rat LOU, also known as Louvain, LOU/C, LOU/M IgG1, κ
克隆号
克隆 R19-15 (RUO)
产品详情
HRP
Horseradish Peroxidase is an enzyme that is capable of cleaving a substrate into hydrogen peroxide which can then be detected in solution or in situ. Antibodies, avidins, and other specific binding molecules conjugated with horseradish peroxidase, in conjunction with an appropriate substrate system, can be used for multiple ELISA or Immunohistochemical applications.
应用
实验应用
ELISA (Routinely Tested)
反应种属
Mouse (QC Testing)
目标/特异性
IgG2a
制备和贮存
存储溶液
Aqueous buffered solution containing BSA and ProClin™ 150 as preservative.
保存方式
Aqueous buffered solution containing BSA and ProClin™ 150 as preservative.
文献
文献
研发参考(2)
1. Martin RM, Silva A, Lew AM. The Igh-1 sequence of the non-obese diabetic (NOD) mouse assigns it to the IgG2c isotype. Immunogenetics. 1997; 46(2):167-168. (Biology).
2. Morgado MG, Cam P, Gris-Liebe C, Cazenave PA, Jouvin-Marche E. Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes. EMBO J. 1989; 8(11):3245-3251. (Biology).
数据库链接
Entrez-Gene ID
380793
参考图片
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