BD Pharmingen- Purified Mouse Anti-Rat RT1A_BD Pharmingen
产品信息
抗原名称
RT1A
宿主
Mouse BALB/c IgG1, κ
免疫原
RT1B-depleted membrane glycoproteins isolated from Wistar rat spleen
简单描述
The OX-18 monoclonal antibody specifically recognizes a non-polymorphic determinant of rat MHC class I antigen on erythrocytes and most nucleated cells, except normal neurons and glial cells. The OX-18 antibody has been reported to block the recognition of RT1A by rat NK cells.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
商品描述
OX-18
The OX-18 monoclonal antibody specifically recognizes a non-polymorphic determinant of rat MHC class I antigen on erythrocytes and most nucleated cells, except normal neurons and glial cells. The OX-18 antibody has been reported to block the recognition of RT1A by rat NK cells.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
同种型
Mouse BALB/c IgG1, κ
克隆号
克隆 OX-18 (RUO)
浓度
0.5 mg/ml
产品详情
Purified
Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.
应用
实验应用
Flow cytometry (Routinely Tested), Blocking, Immunohistochemistry-frozen, Immunoprecipitation (Reported)
反应种属
Rat (QC Testing)
目标/特异性
RT1A
制备和贮存
存储溶液
Aqueous buffered solution containing ≤0.09% sodium azide.
保存方式
Aqueous buffered solution containing ≤0.09% sodium azide.
文献
文献
研发参考(4)
1. Fukumoto T, McMaster WR, Williams AF, et al. Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus. Eur J Immunol. 1982; 12:237-243. (Immunogen: Immunoprecipitation).
2. Kroese FGM. Immunology of the Rat. In: Pastoret PP, Griebel P, Bazin H, Govaerts A, ed. Handbook of Vertebrae Immunology. Academic Press; 1998:137-222.
3. Mason DW, Arthur RP, Dallman MJ, Green JR, Spickett GP, Thomas ML. Functions of rat T-lymphocyte subsets isolated by means of monoclonal antibodies. Immunol Rev. 1983; 74:57-82. (Immunogen: Immunohistochemistry).
4. Neumann H, Cavalie A, Jenne DE, Wekerle H. Induction of MHC class I genes in neurons. Science. 1995; 269(5223):549-552. (Clone-specific).
参考图片
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